分类： 物理学 >> 核物理学 提交时间： 2024-01-03
摘要： Anonlinear dynamic simulation model based on coordinated control of speed and flow rate for the molten salt reactor and combined cycle systems is proposed hereto ensure the coordination and stability between the molten salt reactor and power system. This model considersthe impact of thermal properties of fluid variation on accuracy and has been validated with Simulink. This study reveals the capability of the control system to compensate for anomalous situations and maintain shaft stability in the event of perturbations occurring in high-temperature molten salt tank outlet parameters. Meanwhile, the control system's impact on the system's dynamic characteristicsunder molten salt disturbance is also analyzed. The results reveal that after the disturbance occurs, the controlled systembenefits from the action of the control, and the overshoot and disturbance amplitude are positively correlated while the systempower and frequency eventually return to the initial values. This simulation model provides a basis for utilizing molten salt reactors for power generation and maintaining grid stability.
分类： 天文学 >> 天文学 提交时间： 2024-05-10 合作期刊: 《Research in Astronomy and Astrophysics》
摘要： For the ASO-S/HXI payload, the accuracy of the flare reconstruction is reliant on important factors such as the alignment of the dual grating and the precise measurement of observation orientation. To guarantee optimal functionality of the instrument throughout its life cycle, the Solar Aspect System (SAS) is imperative to ensure that measurements are accurate and reliable. This is achieved by capturing the target motion and utilizing a physical model-based inversion algorithm. However, the SAS optical system's inversion model is a typical ill-posed inverse problem due to its optical parameters, which results in small target sampling errors triggering unacceptable shifts in the solution. To enhance inversion accuracy and make it more robust against observation errors, we suggest dividing the inversion operation into two stages based on the SAS spot motion model. First, the as-rigid-as-possible (ARAP) transformation algorithm calculates the relative rotations and an intermediate variable between the substrates. Second, we solve an inversion linear equation for the relative translation of the substrates, the offset of the optical axes, and the observation orientation. To address the ill-posed challenge, the Tikhonov method grounded on the discrepancy criterion and the maximum a posteriori (MAP) method founded on the Bayesian framework are utilized. The simulation results exhibit that the ARAP method achieves a solution with a rotational error of roughly ±35 (1/2-quantile); both regularization techniques are successful in enhancing the stability of the solution, the variance of error in the MAP method is even smaller—it achieves a translational error of approximately ±18 μm (1/2-quantile) in comparison to the Tikhonov method's error of around ±24 μm (1/2-quantile). Furthermore, the SAS practical application data indicates the method's usability in this study. Lastly, this paper discusses the intrinsic interconnections between the regularization methods.
分类： 生物学 >> 生物物理学 >> 细胞生物学 提交时间： 2016-05-12
Zhang, Hong
Guo, Bin
Lin, Long
Lu, Qun
Wu, Fan
Chang, Jessica T.
Hansen, Malene
Kumsta, Caroline
Lapierre, Louis R.
Jia, Kailiang
Kovacs, Attila L.
Legouis, Renaud
Melendez, Alicia
Melendez, Alicia
O'Rourke, Eyleen J.
Sato, Ken
Sato, Miyuki
Wang, Xiaochen
摘要： The cellular recycling process of autophagy has been extensively characterized with standard assays in yeast and mammalian cell lines. In multicellular organisms, numerous external and internal factors differentially affect autophagy activity in specific cell types throughout the stages of organismal ontogeny, adding complexity to the analysis of autophagy in these metazoans. Here we summarize currently available assays for monitoring the autophagic process in the nematode C. elegans. A combination of measuring levels of the lipidated Atg8 ortholog LGG-1, degradation of well-characterized autophagic substrates such as germline P granule components and the SQSTM1/p62 ortholog SQST-1, expression of autophagic genes and electron microscopy analysis of autophagic structures are presently the most informative, yet steady-state, approaches available to assess autophagy levels in C. elegans. We also review how altered autophagy activity affects a variety of biological processes in C. elegans such as L1 survival under starvation conditions, dauer formation, aging, and cell death, as well as neuronal cell specification. Taken together, C. elegans is emerging as a powerful model organism to monitor autophagy while evaluating important physiological roles for autophagy in key developmental events as well as during adulthood.
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